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湖南省百人计划专家---杨毅教授简介
姓名 |
杨毅 |
性别 |
男 |
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籍贯 |
湖南桃源 |
年龄 |
42 | |||||
学历 |
博士 |
职称 |
教授 | |||||
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yangyi.proc@gmail.com |
电话 |
0731-84635276 18670359397 | |||||
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招 生 意 向 |
招生类型 |
招生学科 |
研究方向 | |||||
硕 士 |
临床兽医学 |
兽医功能蛋白质组学 | ||||||
博 士 |
临床兽医学 |
兽医功能蛋白质组学 | ||||||
兽医硕士 |
兽医学 |
临床兽医学、兽医生物技术 | ||||||
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学 习 经 历 |
1991.09-1995.06,湖南省长沙市,湖南农业大学,园艺专业,大学本科 | |||||||
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研 究 项 目 |
1. 国家自然科学基金 (31270819,杨毅) , Myosin 7a马达蛋白质大分子复合物体外重建及功能研究, 2012.12-2016.12 | |||||||
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代 表 性 论 著 |
Gaowei Hu, Naidong Wang, Wanting Yu, Zhanfeng Wang, Yawen Zou, Yan Zhang, Aibing Wang, Zhibang Deng,Yi Yang*,Generation and immunogenicity of porcine circovirus type 2 chimeric virus-like particles displaying porcine reproductive and respiratory syndrome virus GP5 epitope B,Vaccine,2016,34(16):1896–1903 Zhe Zhu, Naidong Wang, Yang Zhan, Zhanfeng Wang, Aibing Wang, Zhibang Deng,Yi Yang*,Complete Genome Sequence of Porcine Circovirus Strain 102 with a Novel Mutation, Isolated from Hunan Province, China,Genome Announcements,2015,3(3):e00411-15 Yan Zhang, Zhanfeng Wang, Yang Zhan, Qian Gong, Wanting Yu, Zhibang Deng, Aibing Wang,Yi Yang, Naidong Wang*,Generation of E. coli derived virus-like particles of porcine circovirus type 2 and their use for an indirect IgG Enzyme-Linked Immunosorbent Assay,Archives of Virology,2016,161(6):1485-91 Yang Zhan, Naidong Wang, Zhe Zhu, Zhanfeng Wang, Aibing Wang, Zhibang Deng,Yi Yang*,In silico analyses of antigenicity and surface structure variation of an emerging PCV2b mutant, prevalent in southern China from 2013 to 2015,Journal of General Virology,11 January, 2016,97: 922-933 Lei X, Callaway M, Zhou H,Yang Y, Chen W. Obesity associated Lyplal1 gene is regulated in diet induced obesity but not required for adipocyte differentiation.Mol Cell Endocrinol. 2015. 411:207-13. Yang Y, Baboolal TG, Siththanandan V. A FERM domain autoregulates Drosophila myosin 7a activity.The Proceedings of National Academy of Sciences, USA, 2009, 106(11):4189-94. Yang Y, Kovacs M., Sakamoto T, Zhang F, Kiehart DP, Sellers J.R. Dimerized Drosophila myosin VIIa: A processive motor.The Proceedings of National Academy of Sciences, USA. 2006, 11; 103(15):5746-51. Yang Y, Kovacs M, Xu Q, Anderson JB, and Sellers JR. Myosin VIIB from Drosophila is a high duty ratio motor.Journal of Biological Chemistry. 2005, 16; 280(37):32061-8. Takagi Y,Yang Y, Fujiwara I, Jacobs D, Cheney RE, Sellers JR, Kovacs M. Human myosin Vc is a low duty ratio, non-processive molecular motor.Journal of Biological Chemistry. 2008, 283(13):8527-37. Billington N, Beach JR, Heissler SM, Remmert K, Guzik-Lendrum S, Nagy A, Takagi Y, Shao L, Li D,Yang Y, Zhang Y, Barzik M, Betzig E, Hammer JA 3rd, Sellers JR. Myosin 18A coassembles with nonmuscle myosin 2 to form mixed bipolar filaments. Curr Biol.2015. 25(7):942-8. Takagi Y, Farrow RE, Billington N, Nagy A, Batters C,Yang Y, Sellers JR and Molloy JE. Myosin-10 produces its power-stroke in two phases and moves processively along a single actin filament under low load. The Proceedings of National Academy of Sciences, USA. 2014, (10): E1833-42. Guzik-Lendrum S, Heissler SM, Billington N, Takagi Y,Yang Y, Knight PJ, Homsher E, Sellers JR. Mammalian myosin-18A, a highly divergent myosin. Journal Biological Chemistry. 2013, 288(13): 9532-48. Riazuddin S, Nazli S, Ahmed M,Yang Y, et al. Mutation Spectrum of MYO7A and Evaluation of a Novel Nonsyndromic Deafness DFNB2 Allele with Residual Function.Human Mutation. 2008, 29(4):502-11.
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代 表 性 成 果 |
一种猪圆环病毒2型快速分型检测,ZL201310162390.8,中国,2014 杂交瘤细胞、PCV2单克隆抗体及其应用,201410712094.5(实审),中国,2014 一种PCV2病毒样颗粒及其制备方法和裂解及VLP组装缓冲液,ZL201410145870.8,中国,2014 2009年美国卫生部(生物医学研究)杰出贡献奖 美国卫生部国立卫生研究院年度科研优秀个人奖(2003, 2005-2010) 2014年中国畜牧兽医学会优秀论文奖:一种包含PRRSV结构蛋白GP5抗原表位的嵌合VLPS构建与分析 (论文指导教师) | |||||||
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社 会 兼 职 |
美国生物物理学会会员、美国细胞生物学会会员。 Journal of Cellular Biochemistry、Molecula and Cellular Biochemistry等国外重要学术期刊审稿专家 | |||||||
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